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Braz. j. infect. dis ; 9(5): 419-424, Oct. 2005. ilus, tab
Article in English | LILACS | ID: lil-419652

ABSTRACT

Cutaneous manifestations in disseminated strongyloidiasis are infrequent but should raise the suspicion for its diagnosis. We retrospectively evaluated the charts of six patients with cancer and a proven diagnosis of disseminated strongyloidiasis. All patients had received prophylaxis with albendazole before starting antineoplastic therapy, which included high-dose steroids. They presented with septic shock, acute respiratory failure and characteristic purpuric periumbilical skin lesions. Strongyloides larvae were identified in tracheal aspirates (n=5), gastric aspirates (n=4), lung (n=2) and skin biopsies (n=2). All patients died despite antihelminthic therapy and intensive care support.


Subject(s)
Adult , Aged , Animals , Female , Humans , Male , Middle Aged , Neoplasms/parasitology , Neoplasms/pathology , Purpura/pathology , Skin Diseases, Parasitic/pathology , Strongyloides stercoralis/isolation & purification , Strongyloidiasis/pathology , Anthelmintics/therapeutic use , Biopsy , Fatal Outcome , Immunocompromised Host , Neoplasms/immunology , Purpura/immunology , Purpura/parasitology , Skin Diseases, Parasitic/complications , Skin/parasitology , Skin/pathology , Strongyloidiasis/complications , Strongyloidiasis/drug therapy
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